Finding appropriate treatments for autism is a challenge for families and clinicians alike. While behavioral treatments are an effective mainstay of therapeutic approaches, many individuals with autism benefit from the addition of medicinal interventions, particularly for problem behaviors, severe self-injury, and disruptive repetitive behaviors. A major impediment to finding effective treatment regimens is the fact that individual responses to the same medicine can vary greatly due to genetic background. Finding the most effective dose with the fewest side effects means slowly trying various doses, and possibly having to switch medicines. This is not only a challenge for the physician, but is also a confounding factor in large-scale clinical trials that aim to determine the overall effectiveness of a medication.
Posts Tagged ‘Pharmacogenetics’
March 15, 2010 1 comment
This guest post is by Nancy Jones. Nancy Jones, Ph.D. is the Program Director of the Autism Treatment Network and Autism Clinical Trials Networks at Autism Speaks. Nancy received her Ph.D. in Applied Linguistics from the University of California, Los Angeles where she focused on brain and language development in children with developmental disorders.